Record Details

Title Incidence of noncutaneous melanomas in the United States
Author McLaughlin, CC
Secondary Authors Wu XC, Jemal A, Martin HJ, Roche LM, Chen VW
Publication Type (Help) article
Journal Cancer
Month Mar 1
Year 2005
Pages 1000-7
Volume 103
Number 5
Note DOI: 10.1002/cncr.20866
PubMed ID 15651058
EPub Date
Citation McLaughlin CC, Wu XC, Jemal A, Martin HJ, Roche LM, Chen VW. Incidence of noncutaneous melanomas in the United States. Cancer. 2005 Mar 1;103(5):1000-7. PMID 15651058. []


Description of the epidemiology of noncutaneous melanoma has been hampered by its rarity. This report is the largest in-depth descriptive analysis of incidence of noncutaneous melanoma in the United States, using data from NAACCR. Pooled data from 27 states and one metropolitan area were used to examine the incidence of noncutaneous melanoma by anatomic sub-site, gender, age, race and geography (northern/southern and coastal/non coastal) for cases diagnosed between 1996 and 2000. Percent distribution by stage of disease at diagnosis and histology was also examined. Between 1996 and 2000, 6,691 cases of noncutaneous melanoma (4,885 ocular and 1,806 mucosal) were diagnosed among 851 million person years at risk. Ocular melanoma was more common among men compared to women (6.8 cases per million men compared to 5.3 cases per million women, age-adjusted to the 2000 U.S. population standard), whereas mucosal melanoma was more common among women (2.8 cases per million women compared to 1.5 cases per million men). Rates of ocular melanoma among whites were more than eight times higher than among blacks. Rates of mucosal melanoma were approximately two times higher among whites compared to blacks. In contrast to cutaneous melanoma, there was no apparent pattern of increased noncutaneous melanoma among residents of southern or coastal states, with the exception of melanoma of the ciliary body and iris. Despite their shared cellular origins, both ocular and mucosal melanomas differ from cutaneous melanoma in terms of incidence by gender, race and geographic area.


united states